The Stem Cell Connection of Pituitary Tumors

The Stem Cell Connection of Pituitary Tumors

Tumors in the pituitary gland are typically benign but cause serious morbidity due to compression of neighboring structures and hormonal disruptions. Overall, therapy efficiency remains suboptimal with negative impact on health and comfort of life, including considerable risk of therapy resistance and tumor recurrence. To date, little is known on the pathogenesis of pituitary tumors. Stem cells...

The STem Cell ConneCTion of Primary Brain TumorS

Gliomas account for more than half of adult primary intracranial tumors, with anaplastic astrocytomas and glioblastoma multiforme (also known as malignant gliomas) being the most common. Plethora of evidence supports the notion that malignant glioma and other types of primary brain tumors arise from cells with stem cell/progenitor cell properties. To designate this cellular population a novel t...

Outcome of Transphenoid Surgery for Corticotroph Pituitary Tumors

Background & Importance: The aim of this study was to demonstrate the result of transsphenoid microsurgery for Cushing disease in our center and comparing the results in details with other articles, to achieve the best decision for patients management in future. Case Presentation: Between 1991 to 2015, 50 patients suffering from Cushing disease were operated. Before operation, endocrine t...

Pituitary tumors.

Pituitary tumors in the elderly.

The proportion of elderly subjects is growing in Western countries and, as a consequence, several diseases are now recognized with increasing frequency in the older segment of the population. Pituitary tumors are no exception to the rule. However, the presentation, diagnosis and management of pituitary tumors in the elderly, defined as patients older than 65 or 70 years depending on the differe...